A Skype wireless headphone with a mic typically features Bluetooth or a 2.4GHz wireless connection, noise-canceling technology for clear calls, a comfortable lightweight design, and a long-lasting battery. Key features often include a mute button for privacy, multipoint connectivity for connecting to multiple devices, and universal compatibility with platforms like Skype, Zoom, and Teams. Some models may also come with a USB dongle for devices without Bluetooth and an option for a wired connection.